I heard last night on E! (my favorite news source) that Oprah blew out her thyroid which attributed to her weight gain and hiatus from the show for a month! Apparently she had hyperthyroidism then hypothyroidism.
http://www.cbsnews.com/stories/2007/10/17/earlyshow/health/main3377868.shtml?source=mostpop_story
http://www.cbsnews.com/stories/2007/10/17/earlyshow/health/main3377868.shtml?source=mostpop_story
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